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Computational design of medicinal compounds to inhibit RBD-hACE2 interaction in the Omicron variant: unveiling a vulnerable target site

The COVID-19 pandemic, caused by SARS-CoV-2, has globally affected both human health and economy. Several variants with a high potential for reinfection and the ability to evade immunity were detected shortly after the initial reported case of COVID-19. A total of 30 mutations in the spike protein (...

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Detalles Bibliográficos
Autores principales: Shahab, Muhammad, Akter, Shahina, Sarkar, Md Murshed Hasan, Banu, Tanjina Akhtar, Goswami, Barna, Chowdhury, Sanjana Fatema, Naser, Showti Raheel, Habib, Md Ahashan, Shaikh, Aftab Ali, Saki, Morteza, Zheng, Guojun, Khan, Md Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210851/
https://www.ncbi.nlm.nih.gov/pubmed/37265644
http://dx.doi.org/10.1016/j.imu.2023.101281