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Analysis of genome instability and implications for the consequent phenotype in Plasmodium falciparum containing mutated MSH2-1 (P513T)

Malarial parasites exhibit extensive genomic plasticity, which induces the antigen diversification and the development of antimalarial drug resistance. Only a few studies have examined the genome maintenance mechanisms of parasites. The study aimed at elucidating the impact of a mutation in a DNA mi...

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Detalles Bibliográficos
Autores principales: Honma, Hajime, Takahashi, Nobuyuki, Arisue, Nobuko, Sugishita, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210953/
https://www.ncbi.nlm.nih.gov/pubmed/37083479
http://dx.doi.org/10.1099/mgen.0.001003