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Single nucleotide variants in Pseudomonas aeruginosa populations from sputum correlate with baseline lung function and predict disease progression in individuals with cystic fibrosis

The severity and progression of lung disease are highly variable across individuals with cystic fibrosis (CF) and are imperfectly predicted by mutations in the human gene CFTR, lung microbiome variation or other clinical factors. The opportunistic pathogen Pseudomonas aeruginosa (Pa) dominates airwa...

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Detalles Bibliográficos
Autores principales: Saber, Morteza M., Donner, Jannik, Levade, Inès, Acosta, Nicole, Parkins, Michael D., Boyle, Brian, Levesque, Roger C., Nguyen, Dao, Shapiro, B. Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210962/
https://www.ncbi.nlm.nih.gov/pubmed/37052589
http://dx.doi.org/10.1099/mgen.0.000981