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Single nucleotide variants in Pseudomonas aeruginosa populations from sputum correlate with baseline lung function and predict disease progression in individuals with cystic fibrosis
The severity and progression of lung disease are highly variable across individuals with cystic fibrosis (CF) and are imperfectly predicted by mutations in the human gene CFTR, lung microbiome variation or other clinical factors. The opportunistic pathogen Pseudomonas aeruginosa (Pa) dominates airwa...
Autores principales: | Saber, Morteza M., Donner, Jannik, Levade, Inès, Acosta, Nicole, Parkins, Michael D., Boyle, Brian, Levesque, Roger C., Nguyen, Dao, Shapiro, B. Jesse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210962/ https://www.ncbi.nlm.nih.gov/pubmed/37052589 http://dx.doi.org/10.1099/mgen.0.000981 |
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