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Regulatory Role of Anti-Sigma Factor RsbW in Clostridioides difficile Stress Response, Persistence, and Infection

The anaerobic pathogen Clostridioides difficile, which is a primary cause of antibiotic-associated diarrhea, faces a variety of stresses in the environment and in the mammalian gut. To cope with these stresses, alternative sigma factor B (σ(B)) is employed to modulate gene transcription, and σ(B) is...

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Detalles Bibliográficos
Autores principales: Cheng, Jeffrey K. J., Đapa, Tanja, Chan, Ivan Y. L., MacCreath, Thomas O., Slater, Ross, Unnikrishnan, Meera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210984/
https://www.ncbi.nlm.nih.gov/pubmed/37098979
http://dx.doi.org/10.1128/jb.00466-22