Epigenomic profiling of isolated blood cell types reveals highly specific B cell smoking signatures and links to disease risk

BACKGROUND: Tobacco smoking alters the DNA methylation profiles of immune cells which may underpin some of the pathogenesis of smoking-associated diseases. To link smoking-driven epigenetic effects in specific immune cell types with disease risk, we isolated six leukocyte subtypes, CD14+ monocytes,...

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Detalles Bibliográficos
Autores principales: Wang, Xuting, Campbell, Michelle R., Cho, Hye-Youn, Pittman, Gary S., Martos, Suzanne N., Bell, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211291/
https://www.ncbi.nlm.nih.gov/pubmed/37231515
http://dx.doi.org/10.1186/s13148-023-01507-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211291/
https://www.ncbi.nlm.nih.gov/pubmed/37231515
http://dx.doi.org/10.1186/s13148-023-01507-8

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