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Epigenomic profiling of isolated blood cell types reveals highly specific B cell smoking signatures and links to disease risk
BACKGROUND: Tobacco smoking alters the DNA methylation profiles of immune cells which may underpin some of the pathogenesis of smoking-associated diseases. To link smoking-driven epigenetic effects in specific immune cell types with disease risk, we isolated six leukocyte subtypes, CD14+ monocytes,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211291/ https://www.ncbi.nlm.nih.gov/pubmed/37231515 http://dx.doi.org/10.1186/s13148-023-01507-8 |