Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias and disrupts the fine-tuning of G(i/o) signaling

AIMS: Cardiac contractility, essential to maintaining proper cardiac output and circulation, is regulated by G protein-coupled receptor (GPCR) signaling. Previously, the absence of regulator of G protein signaling (RGS) 2 and 5, separately, was shown to cause G protein dysregulation, contributing to...

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Detalles Bibliográficos
Autores principales: Dahlen, Shelby A., Bernadyn, Tyler F., Dixon, Alethia J., Sun, Bo, Xia, Jingsheng, Owens, Elizabeth A., Osei-Owusu, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211374/
https://www.ncbi.nlm.nih.gov/pubmed/35661621
http://dx.doi.org/10.1016/j.yjmcc.2022.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211374/
https://www.ncbi.nlm.nih.gov/pubmed/35661621
http://dx.doi.org/10.1016/j.yjmcc.2022.05.009

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