A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?

VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous spaces of the placenta, leading to placental malaria (PM). Relatively high polymorphism in VAR2CSA sequences has hindered...

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Detalles Bibliográficos
Autores principales: Doritchamou, Justin Y. A., Renn, Jonathan P., Hviid, Lars, Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Pearls
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212100/
https://www.ncbi.nlm.nih.gov/pubmed/37228009
http://dx.doi.org/10.1371/journal.ppat.1011370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212100/
https://www.ncbi.nlm.nih.gov/pubmed/37228009
http://dx.doi.org/10.1371/journal.ppat.1011370

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