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Cardiac RNase Z edited via CRISPR-Cas9 drives heart hypertrophy in Drosophila

Cardiomyopathy (CM) is a group of diseases distinguished by morphological and functional abnormalities in the myocardium. It is etiologically heterogeneous and may develop via cell autonomous and/or non-autonomous mechanisms. One of the most severe forms of CM has been linked to the deficiency of th...

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Detalles Bibliográficos
Autores principales: Migunova, Ekaterina, Rajamani, Saathvika, Bonanni, Stefania, Wang, Fei, Zhou, Chao, Dubrovsky, Edward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212119/
https://www.ncbi.nlm.nih.gov/pubmed/37228086
http://dx.doi.org/10.1371/journal.pone.0286214