Tetra-O-methyl-nordihydroguaiaretic acid inhibits energy metabolism and synergistically induces anticancer effects with temozolomide on LN229 glioblastoma tumors implanted in mice while preventing obesity in normal mice that consume high-fat diets

Tetra-O-methyl-nordihydroguaiaretic acid (terameprocol; M(4)N), a global transcription inhibitor, in combination with a second anticancer drug induces strong tumoricidal activity and has the ability to suppress energy metabolism in cultured cancer cells. In this study, we showed that after continuou...

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Detalles Bibliográficos
Autores principales: Kimura, Kotohiko, Chun, Jong Ho, Lin, Yu-Ling, Liang, Yu-Chuan, Jackson, Tiffany L. B., Huang, Ru Chih C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212158/
https://www.ncbi.nlm.nih.gov/pubmed/37228120
http://dx.doi.org/10.1371/journal.pone.0285536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212158/
https://www.ncbi.nlm.nih.gov/pubmed/37228120
http://dx.doi.org/10.1371/journal.pone.0285536

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