Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy

Chronic myeloid leukemia (CML) is a blood cancer characterized by dysregulated production of maturing myeloid cells driven by the product of the Philadelphia chromosome, the BCR-ABL1 tyrosine kinase. Tyrosine kinase inhibitors (TKIs) have proved effective in treating CML, but there is still a cohort...

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Detalles Bibliográficos
Autores principales: Rodriguez, Jonathan, Iniguez, Abdon, Jena, Nilamani, Tata, Prasanthi, Liu, Zhong-Ying, Lander, Arthur D, Lowengrub, John, Van Etten, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212564/
https://www.ncbi.nlm.nih.gov/pubmed/37115622
http://dx.doi.org/10.7554/eLife.84149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212564/
https://www.ncbi.nlm.nih.gov/pubmed/37115622
http://dx.doi.org/10.7554/eLife.84149

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