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Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide trimming
To appropriately defend against a wide array of pathogens, humans somatically generate highly diverse repertoires of B cell and T cell receptors (BCRs and TCRs) through a random process called V(D)J recombination. Receptor diversity is achieved during this process through both the combinatorial asse...
Autores principales: | Russell, Magdalena L, Simon, Noah, Bradley, Philip, Matsen, Frederick A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212571/ https://www.ncbi.nlm.nih.gov/pubmed/37227256 http://dx.doi.org/10.7554/eLife.85145 |
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