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Extracellular Vesicle–associated GARP/TGFβ:LAP Mediates “Infectious” Allo-tolerance

Here we test the hypothesis that, like CD81-associated “latent” IL35, the transforming growth factor (TGF)β:latency-associated peptide (LAP)/glycoprotein A repetitions predominant (GARP) complex was also tethered to small extracellular vesicles (sEVs), aka exosomes, produced by lymphocytes from allo...

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Detalles Bibliográficos
Autores principales: Burlingham, William J., Jankowska-Gan, Ewa, Fechner, John H., Little, Christopher J., Wang, Jianxin, Hong, Seungpyo, Molla, Miraf, Sullivan, Jeremy A., Foley, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212611/
https://www.ncbi.nlm.nih.gov/pubmed/37250483
http://dx.doi.org/10.1097/TXD.0000000000001475