Relative Change in Donor-Derived Cell-free DNA is Superior to Absolute Values for Diagnosis of Acute Lung Allograft Dysfunction

Donor-derived cell-free DNA (dd-cfDNA%) is a biomarker of early acute lung allograft dysfunction (ALAD), with a value of ≥1.0% indicating injury. Whether dd-cfDNA% is a useful biomarker in patients >2 y posttransplant is unknown. Our group previously demonstrated that median dd-cfDNA% in lung rec...

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Detalles Bibliográficos
Autores principales: Trindade, Anil J., Chapin, Kaitlyn C., Gray, Jennifer N., Furuya, Yuka, Mullican, Amy, Hoy, Haley, Demarest, Caitlin T., Robbins, Ivan M., Bacchetta, Matthew, Erasmus, David B., Shaver, Ciara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Lung Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212612/
https://www.ncbi.nlm.nih.gov/pubmed/37250487
http://dx.doi.org/10.1097/TXD.0000000000001487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212612/
https://www.ncbi.nlm.nih.gov/pubmed/37250487
http://dx.doi.org/10.1097/TXD.0000000000001487

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