Ex vivo factor VIII‐modified proliferating human hepatocytes therapy for haemophilia A

Ex vivo gene manipulation in human hepatocytes is a promising therapeutic strategy in the treatment of inherited liver diseases. However, a major limitation is the lack of a highly efficient and safe genetic manipulation system for transplantable primary human hepatocytes (PHHs). Here, we reported t...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Wu, Ning, Cen, Jing, Li, Jie, Wang, Zhen, Xia, Qiang, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212703/
https://www.ncbi.nlm.nih.gov/pubmed/37199059
http://dx.doi.org/10.1111/cpr.13467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212703/
https://www.ncbi.nlm.nih.gov/pubmed/37199059
http://dx.doi.org/10.1111/cpr.13467

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