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SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageing

Sarcopenia, a skeletal muscle disorder in which loss of muscle mass and function progresses with age, is associated with increased overall frailty, risk of falling and mortality in the elders. Here, we reveal that SESN1 safeguards skeletal muscle from ageing downstream of the longevity gene FOXO3, w...

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Detalles Bibliográficos
Autores principales: Jing, Ying, Zuo, Yuesheng, Sun, Liang, Yu, Zheng‐Rong, Ma, Shuai, Hu, Huifang, Zhao, Qian, Huang, Daoyuan, Zhang, Weiqi, Belmonte, Juan Carlos Izpisua, Yu, Yang, Qu, Jing, Liu, Guang‐Hui, Wang, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212707/
https://www.ncbi.nlm.nih.gov/pubmed/37199024
http://dx.doi.org/10.1111/cpr.13455