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Identification and characterization of the long non-coding RNA NFIA-AS2 as a novel locus for body mass index in American Indians

BACKGROUND: Genome-wide association studies have shown that body mass index (BMI), an estimate of obesity, is highly polygenic. Individual variants typically have small effect sizes, making it challenging to identify unique loci in under-represented ethnic groups which lack statistical power due to...

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Detalles Bibliográficos
Autores principales: Bandesh, Khushdeep, Traurig, Michael, Chen, Peng, Hsueh, Wen-Chi, Hanson, Robert L., Piaggi, Paolo, Baier, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212757/
https://www.ncbi.nlm.nih.gov/pubmed/36806387
http://dx.doi.org/10.1038/s41366-023-01278-5