Cargando…

CD103(+) regulatory T cells underlie resistance to radio-immunotherapy and impair CD8(+) T cell activation in glioblastoma

Glioblastomas are aggressive primary brain tumors with an inherent resistance to T cell-centric immunotherapy due to their low mutational burden and immunosuppressive tumor microenvironment. Here we report that fractionated radiotherapy of preclinical glioblastoma models induce a tenfold increase in...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Hooren, Luuk, Handgraaf, Shanna M., Kloosterman, Daan J., Karimi, Elham, van Mil, Lotte W.H.G., Gassama, Awa A., Solsona, Beatriz Gomez, de Groot, Marnix H. P., Brandsma, Dieta, Quail, Daniela F., Walsh, Logan A., Borst, Gerben R., Akkari, Leila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212765/ https://www.ncbi.nlm.nih.gov/pubmed/37081259 http://dx.doi.org/10.1038/s43018-023-00547-6

Ejemplares similares

CD103 spurs on suppressors
por: Van Epps, Heather L.
Publicado: (2005)

CD103+ tumor-resident CD8+ T cell numbers underlie improved patient survival in oropharyngeal squamous cell carcinoma
por: Hewavisenti, Rehana, et al.
Publicado: (2020)

Intestinal CD103(+)CD4(+) and CD103(+)CD8(+) T-Cell Subsets in the Gut of Inflammatory Bowel Disease Patients at Diagnosis and During Follow-up
por: Roosenboom, Britt, et al.
Publicado: (2019)

CD103 in the development of experimental asthma
por: Blanchet, Marie-Renee, et al.
Publicado: (2010)

Infiltration and Significance of CD103+CD8+ T Cells in Gastrointestinal Adenocarcinoma
por: Cai, Weisu, et al.
Publicado: (2022)

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment
por: van Hooren, Luuk, et al.
Publicado: (2016)

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer
por: Workel, Hagma H., et al.
Publicado: (2020)

Development of [(89)Zr]Zr-hCD103.Fab01A and [(68)Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET
por: Fan, Xiaoyu, et al.
Publicado: (2023)

Accumulation of CD103(+) CD8(+) T cells in a cutaneous melanoma micrometastasis
por: Hochheiser, Katharina, et al.
Publicado: (2019)

TGF-β: Many Paths to CD103(+) CD8 T Cell Residency
por: Qiu, Zhijuan, et al.
Publicado: (2021)

The origin and development of nonlymphoid tissue CD103(+) DCs
por: Ginhoux, Florent, et al.
Publicado: (2009)

Pivotal role of CD103 in the development of psoriasiform dermatitis
por: Fukui, Takehito, et al.
Publicado: (2020)

A role for CD47 in the development of experimental colitis mediated by SIRPα(+)CD103(−) dendritic cells
por: Fortin, Genevieve, et al.
Publicado: (2009)

CD103 Expression Is Required for Destruction of Pancreatic Islet Allografts by CD8(+) T Cells
por: Feng, Ye, et al.
Publicado: (2002)

CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden
por: van den Bulk, Jitske, et al.
Publicado: (2023)

Influenza-Induced CD103(+) T Resident Memory Cells Exhibit Enhanced Functional Avidity over CD103(−) Memory T Cells in the Mediastinal Lymph Node
por: Crooks, Sequoia D., et al.
Publicado: (2022)

Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
por: Banchereau, Romain, et al.
Publicado: (2021)

Assessing the Role of CD103 in Immunity to an Intestinal Helminth Parasite
por: Mullaly, Sarah C., et al.
Publicado: (2011)

Eribulin mesylate exerts antitumor effects via CD103
por: Oya, Kazumasa, et al.
Publicado: (2023)

CD103(+) Cells and Chemokine Receptor Expression in Breast Cancer
por: Seo, Eun-Hye, et al.
Publicado: (2023)

CD103−CD11b+ dendritic cells regulate the sensitivity of CD4 T cell responses to bacterial flagellin
por: Atif, Shaikh M., et al.
Publicado: (2013)

Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
por: Duhen, Thomas, et al.
Publicado: (2018)

Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review
por: van Bussel, Mark T. J., et al.
Publicado: (2019)

Cytokines and TLR agonists influence the expression of retention integrins CD49a, CD49b and CD103 by T cells
por: Melssen, Marit M, et al.
Publicado: (2015)

Aging impacts CD103(+) CD8(+) T cell presence and induction by dendritic cells in the genital tract
por: Rodriguez‐Garcia, Marta, et al.
Publicado: (2018)

CD103-CD23+ classical hair cell leukemia: A case report and review of the literature
por: Zhao, Hong-li, et al.
Publicado: (2021)

Essential role for CD103 in the T cell–mediated regulation of experimental colitis
por: Annacker, Oliver, et al.
Publicado: (2005)

The Role of CD103(+) Dendritic Cells in the Intestinal Mucosal Immune System
por: Ruane, Darren Thomas, et al.
Publicado: (2011)

Author Correction: Pivotal role of CD103 in the development of psoriasiform dermatitis
por: Fukui, Takehito, et al.
Publicado: (2020)

Integrin α(E)(CD103)β(7) in Epithelial Cancer
por: Hoffmann, Johanna C., et al.
Publicado: (2021)

CD34(+)CD19(−)CD22(+) B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies
por: Bueno, Clara, et al.
Publicado: (2022)

Resident CD8(+) and Migratory CD103(+) Dendritic Cells Control CD8 T Cell Immunity during Acute Influenza Infection
por: Waithman, Jason, et al.
Publicado: (2013)

Changes of CD103-expressing pulmonary CD4(+) and CD8(+) T cells in S. japonicum infected C57BL/6 mice
por: Zhao, Yi, et al.
Publicado: (2019)

Level structure of $^{99,101,103}$Ag observed in the decay of light Cd isotopes
por: Kalshoven, A W B, et al.
Publicado: (1980)

Transcriptional and Functional Analysis of CD1c(+) Human Dendritic Cells Identifies a CD163(+) Subset Priming CD8(+)CD103(+) T Cells
por: Bourdely, Pierre, et al.
Publicado: (2020)

CD31(+), CD38(+), CD44(+), and CD103(+) lymphocytes in peripheral blood, bronchoalveolar lavage fluid and lung biopsy tissue in sarcoid patients and controls
por: Aleksonienė, Regina, et al.
Publicado: (2021)

TGFβR signalling controls CD103(+)CD11b(+) dendritic cell development in the intestine
por: Bain, C. C., et al.
Publicado: (2017)

CD103-CD23+ classical hairy cell leukemia: A case report and review of the literature: Erratum
Publicado: (2022)

Retinoic acid signaling during priming licenses intestinal CD103(+) CD8 T(RM) cell differentiation
por: Qiu, Zhijuan, et al.
Publicado: (2023)

CD8+CD103+ iTregs Inhibit Chronic Graft-versus-Host Disease with Lupus Nephritis by the Increased Expression of CD39
por: Zhang, Xiao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gtjus5anrn7bdc9tnbsr5k7fvf