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Butein inhibits corticosterone-induced apoptosis of Neuro2A cells by maintaining MEK-ERK signaling

Stress-induced overactivation of glucocorticoid signaling may contribute to mental illness by inducing neuronal death and dysfunction. We previously reported that pretreatment with the plant flavonoid butein inhibits corticosterone (CORT)-induced apoptosis of Neuro2A (N2A) cells. In the current stud...

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Detalles Bibliográficos
Autores principales: Ohmoto, Masanori, Takemoto, Masaya, Daikoku, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212788/
https://www.ncbi.nlm.nih.gov/pubmed/37252631
http://dx.doi.org/10.1016/j.ibneur.2023.05.002