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Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts
Patient-derived xenograft (PDX) tumor models are known to maintain the genomic and phenotypic profiles, including the histopathological structures, of the parental tumors. On the other hand, unique enrichment of single-nucleotide variants or copy number aberrations has been reported in several types...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212914/ https://www.ncbi.nlm.nih.gov/pubmed/37231035 http://dx.doi.org/10.1038/s41598-023-35703-6 |