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Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts

Patient-derived xenograft (PDX) tumor models are known to maintain the genomic and phenotypic profiles, including the histopathological structures, of the parental tumors. On the other hand, unique enrichment of single-nucleotide variants or copy number aberrations has been reported in several types...

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Detalles Bibliográficos
Autores principales: Imai, Toshio, Yoshida, Hiroshi, Machida, Yukino, Kuramochi, Mizuki, Ichikawa, Hitoshi, Kubo, Takashi, Takahashi, Mami, Kato, Tomoyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212914/
https://www.ncbi.nlm.nih.gov/pubmed/37231035
http://dx.doi.org/10.1038/s41598-023-35703-6