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Whole exome and transcriptome analysis revealed the activation of ERK and Akt signaling pathway in canine histiocytic sarcoma

Histiocytic sarcoma (HS) is an incurable aggressive tumor, and no consensus has been made on the treatment due to its rare occurrence. Since dogs spontaneously develop the disease and several cell lines are available, they have been advocated as translational animal models. In the present study, the...

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Detalles Bibliográficos
Autores principales: Asada, Hajime, Tani, Akiyoshi, Sakuma, Hiroki, Hirabayashi, Miyuki, Matsumoto, Yuki, Watanabe, Kei, Tsuboi, Masaya, Yoshida, Shino, Harada, Kei, Uchikai, Takao, Goto-Koshino, Yuko, Chambers, James K., Ishihara, Genki, Kobayashi, Tetsuya, Irie, Mitsuhiro, Uchida, Kazuyuki, Ohno, Koichi, Bonkobara, Makoto, Tsujimoto, Hajime, Tomiyasu, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212919/
https://www.ncbi.nlm.nih.gov/pubmed/37231193
http://dx.doi.org/10.1038/s41598-023-35813-1