HDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice

Renal tubular epithelial cells (TECs) play a key role in kidney fibrosis by mediating cycle arrest at G2/M. However, the key HDAC isoforms and the underlying mechanism that are involved in G2/M arrest of TECs remain unclear. Here, we find that Hdac9 expression is significantly induced in the mouse f...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Yang, Yujie, Yang, Fan, Liu, Xiaohan, Zhan, Ping, Wu, Jichao, Wang, Xiaojie, Wang, Ziying, Tang, Wei, Sun, Yu, Zhang, Yan, Xu, Qianqian, Shang, Jin, Zhen, Junhui, Liu, Min, Yi, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212923/
https://www.ncbi.nlm.nih.gov/pubmed/37230975
http://dx.doi.org/10.1038/s41467-023-38771-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212923/
https://www.ncbi.nlm.nih.gov/pubmed/37230975
http://dx.doi.org/10.1038/s41467-023-38771-4

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