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HDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice

Renal tubular epithelial cells (TECs) play a key role in kidney fibrosis by mediating cycle arrest at G2/M. However, the key HDAC isoforms and the underlying mechanism that are involved in G2/M arrest of TECs remain unclear. Here, we find that Hdac9 expression is significantly induced in the mouse f...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang, Yang, Yujie, Yang, Fan, Liu, Xiaohan, Zhan, Ping, Wu, Jichao, Wang, Xiaojie, Wang, Ziying, Tang, Wei, Sun, Yu, Zhang, Yan, Xu, Qianqian, Shang, Jin, Zhen, Junhui, Liu, Min, Yi, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212923/ https://www.ncbi.nlm.nih.gov/pubmed/37230975 http://dx.doi.org/10.1038/s41467-023-38771-4

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