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An Aurora B-RPA signaling axis secures chromosome segregation fidelity

Errors in chromosome segregation underlie genomic instability associated with cancers. Resolution of replication and recombination intermediates and protection of vulnerable single-stranded DNA (ssDNA) intermediates during mitotic progression requires the ssDNA binding protein Replication Protein A...

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Detalles Bibliográficos
Autores principales: Roshan, Poonam, Kuppa, Sahiti, Mattice, Jenna R., Kaushik, Vikas, Chadda, Rahul, Pokhrel, Nilisha, Tumala, Brunda R., Biswas, Aparna, Bothner, Brian, Antony, Edwin, Origanti, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212944/
https://www.ncbi.nlm.nih.gov/pubmed/37230964
http://dx.doi.org/10.1038/s41467-023-38711-2