Cargando…

3-Hydroxybutyrate ameliorates insulin resistance by inhibiting PPARγ Ser273 phosphorylation in type 2 diabetic mice

3-Hydroxybutyrate (3HB) is a small ketone body molecule produced endogenously by the body in the liver. Previous studies have shown that 3HB can reduce blood glucose level in type 2 diabetic (T2D) patients. However, there is no systematic study and clear mechanism to evaluate and explain the hypogly...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yudian, Li, Zihua, Liu, Xinyi, Chen, Xinyu, Zhang, Shujie, Chen, Yuemeng, Chen, Jiangnan, Chen, Jin, Wu, Fuqing, Chen, Guo-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212965/
https://www.ncbi.nlm.nih.gov/pubmed/37230992
http://dx.doi.org/10.1038/s41392-023-01415-6