Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth

The innate immune system has a key role in pancreatic cancer initiation, but the specific contribution of different macrophage populations is still ill-defined. While inflammatory (M1) macrophages have been shown to drive acinar-to-ductal metaplasia (ADM), a cancer initiating event, alternatively ac...

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Detalles Bibliográficos
Autores principales: Liou, Geou-Yarh, Fleming Martinez, Alicia K., Döppler, Heike R., Bastea, Ligia I., Storz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212997/
https://www.ncbi.nlm.nih.gov/pubmed/37250781
http://dx.doi.org/10.1016/j.isci.2023.106820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212997/
https://www.ncbi.nlm.nih.gov/pubmed/37250781
http://dx.doi.org/10.1016/j.isci.2023.106820

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