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Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs

The search for G-quadruplex (G4)-forming sequences across the genome is motivated by their involvement in key cellular processes and their putative roles in dysregulations underlying human genetic diseases. Sequencing-based methods have been developed to assess the prevalence of DNA G4s genome wide,...

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Detalles Bibliográficos
Autores principales: Feng, Yilong, He, Zexue, Luo, Zhenyu, Sperti, Francesco Rota, Valverde, Ibai E., Zhang, Wenli, Monchaud, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10212998/
https://www.ncbi.nlm.nih.gov/pubmed/37250775
http://dx.doi.org/10.1016/j.isci.2023.106846