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Non-canonical telomere protection role of FOXO3a of human skeletal muscle cells regulated by the TRF2-redox axis

Telomeric repeat binding factor 2 (TRF2) binds to telomeres and protects chromosome ends against the DNA damage response and senescence. Although the expression of TRF2 is downregulated upon cellular senescence and in various aging tissues, including skeletal muscle tissues, very little is known abo...

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Detalles Bibliográficos
Autores principales: Jacome Burbano, Maria Sol, Robin, Jérôme D., Bauwens, Serge, Martin, Marjorie, Donati, Emma, Martínez, Lucia, Lin, Peipei, Sacconi, Sabrina, Magdinier, Frédérique, Gilson, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213016/
https://www.ncbi.nlm.nih.gov/pubmed/37231173
http://dx.doi.org/10.1038/s42003-023-04903-1