Cargando…
Non-canonical telomere protection role of FOXO3a of human skeletal muscle cells regulated by the TRF2-redox axis
Telomeric repeat binding factor 2 (TRF2) binds to telomeres and protects chromosome ends against the DNA damage response and senescence. Although the expression of TRF2 is downregulated upon cellular senescence and in various aging tissues, including skeletal muscle tissues, very little is known abo...
Autores principales: | Jacome Burbano, Maria Sol, Robin, Jérôme D., Bauwens, Serge, Martin, Marjorie, Donati, Emma, Martínez, Lucia, Lin, Peipei, Sacconi, Sabrina, Magdinier, Frédérique, Gilson, Eric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213016/ https://www.ncbi.nlm.nih.gov/pubmed/37231173 http://dx.doi.org/10.1038/s42003-023-04903-1 |
Ejemplares similares
-
Mitochondrial function in skeletal myofibers is controlled by a TRF2‐SIRT3 axis over lifetime
por: Robin, Jérôme D., et al.
Publicado: (2020) -
TRF2 Controls Telomeric Nucleosome Organization in a Cell Cycle Phase-Dependent Manner
por: Galati, Alessandra, et al.
Publicado: (2012) -
The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin
por: Bauwens, Serge, et al.
Publicado: (2021) -
TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization
por: Galati, Alessandra, et al.
Publicado: (2015) -
The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging
por: Ying, Yilin, et al.
Publicado: (2022)