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Sex differences in VTA GABA transmission and plasticity during opioid withdrawal

The effectiveness of current treatments for opioid use disorder (OUD) varies by sex. Our understanding of the neurobiological mechanisms mediating negative states during withdrawal is lacking, particularly with regard to sex differences. Based on preclinical research in male subjects, opioid withdra...

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Detalles Bibliográficos
Autores principales: Kalamarides, Daniel J., Singh, Aditi, Wolfman, Shannon L., Dani, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213060/
https://www.ncbi.nlm.nih.gov/pubmed/37231124
http://dx.doi.org/10.1038/s41598-023-35673-9