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704/DNA vaccines leverage cytoplasmic DNA stimulation to promote anti-HIV neutralizing antibody production in mice and strong immune response against alpha-fetoprotein in non-human primates

Genetic immunization is an attractive approach for prophylactic and therapeutic vaccination using synthetic vectors to deliver antigen-encoding nucleic acids. Recently, DNA delivered by a physical means or RNA by liposomes consisting of four different lipids demonstrated good protection in human pha...

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Detalles Bibliográficos
Autores principales: Colombani, Thibault, Haudebourg, Thomas, Pitard, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213191/
https://www.ncbi.nlm.nih.gov/pubmed/37251693
http://dx.doi.org/10.1016/j.omtn.2023.04.029