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Intranasally delivered mesenchymal stromal cells decrease glial inflammation early in prion disease

Mesenchymal stromal cells (MSCs) are an intriguing avenue for the treatment of neurological disorders due to their ability to migrate to sites of neuroinflammation and respond to paracrine signaling in those sites by secreting cytokines, growth factors, and other neuromodulators. We potentiated this...

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Detalles Bibliográficos
Autores principales: Hay, Arielle J. D., Latham, Amanda S., Mumford, Genova, Hines, Amelia D., Risen, Sydney, Gordon, Elizabeth, Siebenaler, Connor, Gilberto, Vincenzo S., Zabel, Mark D., Moreno, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213210/
https://www.ncbi.nlm.nih.gov/pubmed/37250395
http://dx.doi.org/10.3389/fnins.2023.1158408