Effects of a neurokinin-1 receptor antagonist in the acute phase after thoracic spinal cord injury in a rat model

OBJECTIVE: Disruption of the blood-spinal cord barrier (BSCB) with subsequent edema formation and further neuroinflammation contributes to aggravation of spinal cord injury (SCI). We aimed to observe the effect of antagonizing the binding of the neuropeptide Substance-P (SP) to its neurokinin-1 (NK1...

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Detalles Bibliográficos
Autores principales: Zheng, Guoli, Harms, Anna-Kathrin, Tail, Mohamed, Zhang, Hao, Nimmo, Alan, Skutella, Thomas, Kiening, Karl, Unterberg, Andreas, Zweckberger, Klaus, Younsi, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213275/
https://www.ncbi.nlm.nih.gov/pubmed/37251648
http://dx.doi.org/10.3389/fnmol.2023.1128545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213275/
https://www.ncbi.nlm.nih.gov/pubmed/37251648
http://dx.doi.org/10.3389/fnmol.2023.1128545

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