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Recent progress of the genetics of amyotrophic lateral sclerosis and challenges of gene therapy
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord. The causes of ALS are not fully understood. About 10% of ALS cases were associated with genetic factors. Since the discovery of the first familial ALS...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213321/ https://www.ncbi.nlm.nih.gov/pubmed/37250416 http://dx.doi.org/10.3389/fnins.2023.1170996 |