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Engineering circuits of human iPSC-derived neurons and rat primary glia

Novel in vitro platforms based on human neurons are needed to improve early drug testing and address the stalling drug discovery in neurological disorders. Topologically controlled circuits of human induced pluripotent stem cell (iPSC)-derived neurons have the potential to become such a testing syst...

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Detalles Bibliográficos
Autores principales: Girardin, Sophie, Ihle, Stephan J., Menghini, Arianna, Krubner, Magdalena, Tognola, Leonardo, Duru, Jens, Fruh, Isabelle, Müller, Matthias, Ruff, Tobias, Vörös, János
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213452/
https://www.ncbi.nlm.nih.gov/pubmed/37250404
http://dx.doi.org/10.3389/fnins.2023.1103437