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Identification of key factors driving inflammation-induced sensitization of muscle sensory neurons

Sensory neurons embedded in muscle tissue that initiate pain sensations, i.e., nociceptors, are temporarily sensitized by inflammatory mediators during musculoskeletal trauma. These neurons transduce peripheral noxious stimuli into an electrical signal [i.e., an action potential (AP)] and, when sens...

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Detalles Bibliográficos
Autores principales: Nagaraja, Sridevi, Tewari, Shivendra G., Reifman, Jaques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213456/
https://www.ncbi.nlm.nih.gov/pubmed/37250415
http://dx.doi.org/10.3389/fnins.2023.1147437