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A gene-level test for directional selection on gene expression

Most variants identified in human genome-wide association studies and scans for selection are noncoding. Interpretation of their effects and the way in which they contribute to phenotypic variation and adaptation in human populations is therefore limited by our understanding of gene regulation and t...

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Detalles Bibliográficos
Autores principales: Colbran, Laura L, Ramos-Almodovar, Fabian C, Mathieson, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213495/
https://www.ncbi.nlm.nih.gov/pubmed/37036411
http://dx.doi.org/10.1093/genetics/iyad060