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A gene-level test for directional selection on gene expression
Most variants identified in human genome-wide association studies and scans for selection are noncoding. Interpretation of their effects and the way in which they contribute to phenotypic variation and adaptation in human populations is therefore limited by our understanding of gene regulation and t...
Autores principales: | Colbran, Laura L, Ramos-Almodovar, Fabian C, Mathieson, Iain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213495/ https://www.ncbi.nlm.nih.gov/pubmed/37036411 http://dx.doi.org/10.1093/genetics/iyad060 |
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