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Combined analysis of single-cell and bulk RNA sequencing reveals the expression patterns of circadian rhythm disruption in the immune microenvironment of Alzheimer’s disease

BACKGROUND: Circadian rhythm disruption (CRD) represents a critical contributor to the pathogenesis of Alzheimer’s disease (AD). Nonetheless, how CRD functions within the AD immune microenvironment remains to be illustrated. METHODS: Circadian rhythm score (CRscore) was utilized to quantify the micr...

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Detalles Bibliográficos
Autores principales: He, Huiling, Yang, Yingxia, Wang, Lingxing, Guo, Zeming, Ye, Lichao, Ou-Yang, Wanjiong, Yang, Meili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213546/
https://www.ncbi.nlm.nih.gov/pubmed/37251379
http://dx.doi.org/10.3389/fimmu.2023.1182307