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Behavioral effects of triazolam and pregnanolone combinations: reinforcing and sedative-motor effects in female rhesus monkeys

INTRODUCTION: Benzodiazepines (BZs) are prescribed as anxiolytics, but their use is limited by side effects including abuse liability and daytime drowsiness. Neuroactive steroids are compounds that, like BZs, modulate the effects of GABA at the GABA(A) receptor. In a previous study, combinations of...

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Detalles Bibliográficos
Autores principales: Cook, Jemma E., Platt, Donna M., Rüedi-Bettschen, Daniela, Rowlett, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213563/
https://www.ncbi.nlm.nih.gov/pubmed/37252149
http://dx.doi.org/10.3389/fpsyt.2023.1142531