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Apicomplexan parasites are attenuated by low-energy electron irradiation in an automated microfluidic system and protect against infection with Toxoplasma gondii

Radiation-attenuated intracellular parasites are promising immunization strategies. The irradiated parasites are able to invade host cells but fail to fully replicate, which allows for the generation of an efficient immune response. Available radiation technologies such as gamma rays require complex...

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Detalles Bibliográficos
Autores principales: Finkensieper, Julia, Mayerle, Florian, Rentería-Solís, Zaida, Fertey, Jasmin, Makert, Gustavo R., Lange, Franziska, Besecke, Joana, Schopf, Simone, Poremba, Andre, König, Ulla, Standfest, Bastian, Thoma, Martin, Daugschies, Arwid, Ulbert, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213580/
https://www.ncbi.nlm.nih.gov/pubmed/37233817
http://dx.doi.org/10.1007/s00436-023-07880-w