Modeling fibrotic alveolar transitional cells with pluripotent stem cell-derived alveolar organoids

Repeated injury of the lung epithelium is proposed to be the main driver of idiopathic pulmonary fibrosis (IPF). However, available therapies do not specifically target the epithelium and human models of fibrotic epithelial damage with suitability for drug discovery are lacking. We developed a model...

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Detalles Bibliográficos
Autores principales: Ptasinski, Victoria, Monkley, Susan J, Öst, Karolina, Tammia, Markus, Alsafadi, Hani N, Overed-Sayer, Catherine, Hazon, Petra, Wagner, Darcy E, Murray, Lynne A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213712/
https://www.ncbi.nlm.nih.gov/pubmed/37230801
http://dx.doi.org/10.26508/lsa.202201853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213712/
https://www.ncbi.nlm.nih.gov/pubmed/37230801
http://dx.doi.org/10.26508/lsa.202201853

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