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Crystal structures of glycoprotein D of equine alphaherpesviruses reveal potential binding sites to the entry receptor MHC-I

Cell entry of most alphaherpesviruses is mediated by the binding of glycoprotein D (gD) to different cell surface receptors. Equine herpesvirus type 1 (EHV-1) and EHV-4 gDs interact with equine major histocompatibility complex I (MHC-I) to initiate entry into equine cells. We have characterized the...

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Detalles Bibliográficos
Autores principales: Kremling, Viviane, Loll, Bernhard, Pach, Szymon, Dahmani, Ismail, Weise, Christoph, Wolber, Gerhard, Chiantia, Salvatore, Wahl, Markus C., Osterrieder, Nikolaus, Azab, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213783/
https://www.ncbi.nlm.nih.gov/pubmed/37250020
http://dx.doi.org/10.3389/fmicb.2023.1197120