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Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses

RNA viruses continue to remain a threat for potential pandemics due to their rapid evolution. Potentiating host antiviral pathways to prevent or limit viral infections is a promising strategy. Thus, by testing a library of innate immune agonists targeting pathogen recognition receptors, we observe t...

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Detalles Bibliográficos
Autores principales: Garcia, Gustavo, Irudayam, Joseph Ignatius, Jeyachandran, Arjit Vijey, Dubey, Swati, Chang, Christina, Castillo Cario, Sebastian, Price, Nate, Arumugam, Sathya, Marquez, Angelica L., Shah, Aayushi, Fanaei, Amir, Chakravarty, Nikhil, Joshi, Shantanu, Sinha, Sanjeev, French, Samuel W., Parcells, Mark S., Ramaiah, Arunachalam, Arumugaswami, Vaithilingaraja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213809/
https://www.ncbi.nlm.nih.gov/pubmed/37119814
http://dx.doi.org/10.1016/j.xcrm.2023.101024