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Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
RNA viruses continue to remain a threat for potential pandemics due to their rapid evolution. Potentiating host antiviral pathways to prevent or limit viral infections is a promising strategy. Thus, by testing a library of innate immune agonists targeting pathogen recognition receptors, we observe t...
Autores principales: | Garcia, Gustavo, Irudayam, Joseph Ignatius, Jeyachandran, Arjit Vijey, Dubey, Swati, Chang, Christina, Castillo Cario, Sebastian, Price, Nate, Arumugam, Sathya, Marquez, Angelica L., Shah, Aayushi, Fanaei, Amir, Chakravarty, Nikhil, Joshi, Shantanu, Sinha, Sanjeev, French, Samuel W., Parcells, Mark S., Ramaiah, Arunachalam, Arumugaswami, Vaithilingaraja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213809/ https://www.ncbi.nlm.nih.gov/pubmed/37119814 http://dx.doi.org/10.1016/j.xcrm.2023.101024 |
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