Activated tissue resident memory T-cells (CD8+CD103+CD39+) uniquely predict survival in left sided “immune-hot” colorectal cancers

INTRODUCTION: Characterization of the tumour immune infiltrate (notably CD8+ T-cells) has strong predictive survival value for cancer patients. Quantification of CD8 T-cells alone cannot determine antigenic experience, as not all infiltrating T-cells recognize tumour antigens. Activated tumour-speci...

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Detalles Bibliográficos
Autores principales: Talhouni, Shahd, Fadhil, Wakkas, Mongan, Nigel P., Field, Lara, Hunter, Kelly, Makhsous, Sogand, Maciel-Guerra, Alexandre, Kaur, Nayandeep, Nestarenkaite, Ausrine, Laurinavicius, Arvydas, Willcox, Benjamin E., Dottorini, Tania, Spendlove, Ian, Jackson, Andrew M., Ilyas, Mohammad, Ramage, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213916/
https://www.ncbi.nlm.nih.gov/pubmed/37251410
http://dx.doi.org/10.3389/fimmu.2023.1057292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213916/
https://www.ncbi.nlm.nih.gov/pubmed/37251410
http://dx.doi.org/10.3389/fimmu.2023.1057292

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