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Effect of P2Y12 Inhibitors on Organ Support–Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial

IMPORTANCE: Platelet activation is a potential therapeutic target in patients with COVID-19. OBJECTIVE: To evaluate the effect of P2Y12 inhibition among critically ill patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS: This international, open-label, adaptive platform, 1:1 random...

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Detalles Bibliográficos
Autores principales: Berger, Jeffrey S., Neal, Matthew D., Kornblith, Lucy Z., Gong, Michelle N., Reynolds, Harmony R., Cushman, Mary, Althouse, Andrew D., Lawler, Patrick R., McVerry, Bryan J., Kim, Keri S., Baumann Kreuziger, Lisa, Solomon, Scott D., Kosiborod, Mikhail N., Berry, Scott M., Bochicchio, Grant V., Contoli, Marco, Farkouh, Michael E., Froess, Joshua D., Gandotra, Sheetal, Greenstein, Yonatan, Hade, Erinn M., Hanna, Nicholas, Hudock, Kristin, Hyzy, Robert C., Ibáñez Estéllez, Fátima, Iovine, Nicole, Khanna, Ashish K., Khatri, Pooja, Kirwan, Bridget-Anne, Kutcher, Matthew E., Leifer, Eric, Lim, George, Lopes, Renato D., Lopez-Sendon, Jose L., Luther, James F., Nigro Maia, Lilia, Quigley, John G., Wahid, Lana, Wilson, Jennifer G., Zarychanski, Ryan, Kindzelski, Andrei, Geraci, Mark W., Hochman, Judith S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214036/
https://www.ncbi.nlm.nih.gov/pubmed/37227729
http://dx.doi.org/10.1001/jamanetworkopen.2023.14428