Harnessing endogenous transcription factors directly by small molecules for chemically induced pluripotency inception

Chemistry-alone approach has recently been applied for incepting pluripotency in somatic cells, representing a breakthrough in biology. However, chemical reprogramming is hampered by low efficiency, and the underlying molecular mechanisms remain unclear. Particularly, chemical compounds do not have...

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Detalles Bibliográficos
Autores principales: Jin, Yan, Lu, Yunkun, Lin, Lianyu, Liu, Chao, Ma, Xiaojie, Chen, Xi, Zhou, Ziyu, Hu, Zhensheng, Pu, Jiaqi, Chen, Guo, Deng, Qian, Jiang, Liling, Li, Yuhan, Zhao, Yulong, Wang, Hao, Fu, Junfen, Li, Wei, Zhu, Saiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214147/
https://www.ncbi.nlm.nih.gov/pubmed/37192170
http://dx.doi.org/10.1073/pnas.2215155120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214147/
https://www.ncbi.nlm.nih.gov/pubmed/37192170
http://dx.doi.org/10.1073/pnas.2215155120

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