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vPIF-1 is an insulin-like antiferroptotic viral peptide

Iridoviridae, such as the lymphocystis disease virus-1 (LCDV-1) and other viruses, encode viral insulin–like peptides (VILPs) which are capable of triggering insulin receptors (IRs) and insulin-like growth factor receptors. The homology of VILPs includes highly conserved disulfide bridges. However,...

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Detalles Bibliográficos
Autores principales: Belavgeni, Alexia, Maremonti, Francesca, Tonnus, Wulf, Stadtmüller, Marlena, Gavali, Shubhangi, Mallais, Melodie, Flade, Karolin, Brucker, Anne, Becker, Jorunn Naila, Beer, Kristina, Tmava, Mirela, Stumpf, Julian, Gembardt, Florian, Hugo, Christian, Giacca, Mauro, Hale, Benjamin G., Perakakis, Nikolaos, Sha, Wei, Pratt, Derek A., Schally, Andrew V., Bornstein, Stefan R., Linkermann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214148/
https://www.ncbi.nlm.nih.gov/pubmed/37186845
http://dx.doi.org/10.1073/pnas.2300320120